Translational informatics research for decision support in biomedicine

Start: 12/14/2012 1:30 pm
End: 12/14/2012 3:30 pm

Departmental Colloquium

Dr. Alfredo Tirado-Ramos
<http://www.cfar.emory.edu/bio/investigator/tirado-ramos.html>
Assistant Professor
Biomedical Informatics Department
School of Medicine
Emory University


Decision support is a broad field that aims to help people in making good
decisions in complex environments. One of the tools available to scientists,
informatics, provides languages to study and understand complex multiscale,
multiscience systems, based on a fixed universe of possibilities that
considers the "known knowns" and the "known unknowns", rooted in the early
work on foundations of decision making by Von Neumann and Morgenstern.
Computer-based decision support has been widely applied in economics,
psychology, philosophy, mathematics, and statistics knowledge-based systems.
Good examples of such systems include rule-based reasoning methodologies and
simulation-based scenarios, quite popular in biomedical science.

When it comes to human systems, though, things tend to get complex. Humans
include unique and distinguishable components, all the way from biological
cells made of thousands of molecules to our society of more than 6 billion
interacting individuals. The complete cascade from genome to health forms
multi-scale systems and crosses many orders of magnitude in temporal and
spatial scales. Understanding, quantifying, and handling this complexity are
some of the biggest scientific challenges of our time. In this talk we
highlight the importance of this challenge and show a couple of biomedical
decision support use cases where bioinformatics, health informatics and
public health informatics bridge knowledge from each other, from laboratory
bench to patient bedside.

About the Speaker: Dr. Alfredo Tirado-Ramos holds appointments at Emory
University as Assistant Professor at the Department of Biomedical
Informatics, School of Medicine, Adjunct Assistant Professor at the
Department of Mathematics and Computer Science, College of Arts and
Sciences, and as Senior Scientist at the Emory Center for Comprehensive
Informatics. He regularly chairs committees in international conferences on
computing in biomedicine and the life sciences, as well as teaching
computational science. He also currently directs the Emory Center for AIDS
Research Biomedical Informatics Core and is an active member of the the
Winship Cancer Institute's Control and Population Science Program, and his
current research interests focus on decision support for system level eScience.
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yanqing