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Subject:
From:
Tammie Dudley <[log in to unmask]>
Reply To:
MS Student <[log in to unmask]>
Date:
Thu, 3 Nov 2011 08:54:14 -0400
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Seminar on Friday, Nov. 4, at 2PM in CS Conference Room


Title: "HiFi  A Computer Program for Haplotype imputation From incomplete data"

Qing Song, MD PhD
Assistant Professor
Cardiovascular Research Institute
Morehouse School of Medicine
720 Westview Dr SW
Atlanta, GA 30310

Summary: Currently computational haplotyping methods are limited by inaccuracies, ambiguities, and short phasing distance, and experimental methods are limited by labor, cost and incompleteness. Here, we report a computational/experimental integrated method to solve the single-individual haplotyping problem. We implemented this method into a software (HiFi) and applied for resolving the chromosomal haplotypes of 14 individuals. Each genome haplotype were determined in 2.5 minute completely on all SNPs, with ~99.7% accuracy.

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